• Addresses timely topics alongside foundational basic science for an in-depth and comprehensive understanding of the field
• Contains thoroughly up-to-date content, including two new chapters: The Immune System: Implications for Anesthetic Management and Emergency Preparedness in Healthcare
• Provides new content in key areas such as sustainability, global health equity, the effect of anesthetics on immune function, anesthesia for special populations, coverage of infectious diseases including COVID-19, and occupational exposure and safety
• Offers state-of-the-art coverage of anesthetic drugs, guidelines for anesthetic practice and patient safety, new techniques, step-by-step instructions for patient management, the unique needs of pediatric patients, and much more—all highlighted by more than 1,200 full-color illustrations (300 new to this edition) for enhanced visual clarity
• Includes 40+ video clips demonstrating patient positioning, ultrasound, echocardiograms, and other imaging, and anesthetic procedures in real time
• An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

Table of contents

VOLUME 1

SECTION I Introduction

1. The Scope of Modern Anesthetic Practice
2. Anesthesia and Global Health Equity
3. Perioperative Medicine
4. Informatics in Perioperative Medicine
5. Quality Improvement in Anesthesia Practice and Patient Safety
6. Human Behavior and Simulation in Anesthesia
7. Ethical Aspects of Anesthesia Care

SECTION II Anesthetic Physiology

8. Consciousness, Memory, and Anesthesia
9. Sleep Medicine
10. Cerebral Physiology and the Effects of Anesthetic Drugs
11. Neuromuscular Physiology and Pharmacology
12. Respiratory Physiology and Pathophysiology
13. Cardiac Physiology
14. Gastrointestinal and Hepatic Physiology, Pathophysiology, and Anesthetic Considerations
15. Renal Anatomy, Physiology, Pharmacology, and Evaluation of Function
16. Basic Principles of Pharmacology
17. Inhaled Anesthetics: Mechanisms of Action
18. Inhaled Anesthetic Uptake, Distribution, Metabolism, and Toxicity
19. Pulmonary Pharmacology of Inhaled Anesthetics
20. Inhaled Anesthetic Delivery Systems
21. Intravenous Anesthetics
22. Opioids
23. Intravenous Drug Delivery Systems
24. Pharmacology of Neuromuscular Blocking Drugs and Antagonists (Reversal Agents)
25. Local Anesthetics
26. Immune Implications of Anesthesia Care and Practice

SECTION III Anesthesia Management

27. Risk of Anesthesia
28. Preoperative Evaluation
29. Anesthetic Implications of Concurrent Diseases
30. Patient Positioning and Associated Risks
31. Neuromuscular Disorders and Other Genetic Disorders
32. Cardiovascular Monitoring
33. Perioperative Echocardiography and Point-of-Care Ultrasound (POCUS)
34. Implantable Cardiac Pulse Generators: Pacemakers and Cardioverter-Defibrillators
35. Neurophysiologic Monitoring
36. Monitoring the Brain’s Response to Anesthesia and Surgery
37. Respiratory Monitoring
38. Renal Pathophysiology and Treatment for Perioperative Ischemia and Nephrotoxic Injury
39. Neuromuscular Monitoring
40. Airway Management in the Adult
41. Spinal, Epidural, and Caudal Anesthesia
42. Peripheral Nerve Blocks and Ultrasound Guidance for Regional Anesthesia
43. Perioperative Fluid and Electrolyte Therapy
44. Perioperative Acid–Base Balance
45. Patient Blood Management: Transfusion Therapy
46. Patient Blood Management: Coagulation

VOLUME 2

SECTION IV Adult Subspecialty Management

47. Management of the Patient with Chronic Pain
48. Palliative Medicine
49. Anesthesia for Thoracic Surgery
50. Anesthesia for Cardiac Surgical Procedures
51. Anesthesia for Correction of Cardiac Arrhythmias
52. Anesthesia for Vascular Surgery
53. Anesthesia for Neurologic Surgery and Neurointerventions
54. Anesthesia for Bariatric Surgery
55. Anesthesia and the Renal and Genitourinary Systems
56. Anesthesia for Abdominal Organ Transplantation
57. Anesthesia for Organ Procurement
58. Anesthesia for Obstetrics
59. Anesthesia for Fetal Surgery and Other Fetal Therapies
60. Anesthesia for Orthopedic Surgery
61. Geriatric Anesthesia
62. Anesthesia for Trauma
63. Prehospital Care for Medical Emergencies and Trauma
64. Biologic, Natural, and Human-Induced Disasters: The Role of the Anesthesiologist
65. Anesthesia for Ophthalmic Surgery
66. Anesthesia for Otolaryngologic and Head–Neck Surgery
67. Anesthesia for Robotic Surgery
68. Ambulatory (Outpatient) Anesthesia
69. Non–Operating Room Anesthesia
70. Clinical Care in Extreme Environments: Physiology at High Altitude and in Space
71. Clinical Care in Extreme Environments: High Pressure, Immersion, Drowning, Hypo-, and Hyperthermia

SECTION V Pediatric Anesthesia

72. Pediatric Anesthesia
73. Anesthesia for Pediatric Cardiac Surgery
74. Regional Anesthesia in Children
75. Pediatric and Neonatal Critical Care

SECTION VI Postoperative Care

76. The Postanesthesia Care Unit
77. Acute Postoperative Pain
78. Perioperative Neurocognitive Disorders

SECTION VII Critical Care Medicine

79. Critical Care Anesthesiology
80. Neurocritical Care
81. Extracorporeal Membrane Oxygenation and Cardiac Devices
82. Cardiopulmonary Resuscitation and Advanced Cardiac Life Support

SECTION VIII Ancillary Responsibilities and Problems

83. Burn Management
84. Occupational Safety, Infection Control, and Substance Use Disorders
85. Emergency Preparedness in Health Care
86. Clinical Research
87. Interpreting the Medical Literature